Inventaire
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DEWACHTER Laurence



Units

Laboratory of Physiology and Pharmacology

Cardiac fibrosis (Prof. N. Baeyens) - Cardiovascular biomechanics and vascular remodeling (Prof. N. Baeyens) - Physiopathology of the cardiovascular system and pulmonary circulation (Prof. K. Mc Entee, Dr. L. Dewachter) - Dental sciences and oral health (Prof. S. Cetik and Prof. N. Baeyens) - Bioelectricity (Prof. A. Boom and Prof. R. Beauwens) - Cardiac surgery (Prof. Vanden Eynden)

Projetcs

Pulmonary circulation and myocardium

Translational projects to better understand pathogenesis of pulmonary hypertension, lung vascular remodeling and effects on the myocardium in order to identify new therapeutic targets. Current projects relate to: (a) the effects of adipokines (leptin and chemerin) and of BMPR2 and endothelin-1 signaling pathways on endothelial dysfunction, remodeling and intercellular communication within the pulmonary arteriolar wall; (b) the pathogenesis of right heart failure and the role of SDF-1; (c) the impact of brain death on pulmonary circulation and right heart.