Units

Laboratory of Stem Cells & Cancer

Funded in 2006 by Prof. Cédric Blanpain, the Laboratory of Stem Cells and Cancer uses lineage-tracing approaches to study the role of stem cells during development, homeostasis and cancer. They uncovered the existence of stem cells dynamic acting during development, homeostasis and repair of the epidermis and uncovered a novel paradigm of lineage segregation in the mammary gland and prostate. They were pioneered in the identification of cellular origin of cancer in skin carcinoma and mammary tumors. The Laboratory of Stem Cells and Cancer developed novel approaches to unravel tumor heterogeneity and to understand the mechanisms regulating the tumor states responsible for tumor growth, metastasis and resistance to anti-cancer therapy.

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