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Laboratory of Stem Cells & Cancer

Faculty of Medicine | Erasme Campus

Interfaculty institutes | IB²: Interuniversity Institute of Bioinformatics of Brussels

Interfaculty institutes | U-CRC: ULB Cancer Research Center

(Code: ULB779)

Person in charge of the unit : BLANPAIN Cédric.

Funded in 2006 by Prof. Cédric Blanpain, the laboratory of stem cells & cancer uses lineage-tracing approaches to study the role of SCs during
development, homeostasis and cancer. They uncovered the existence of stem cells and progenitors acting during homeostasis and repair of the epidermis and uncovered a
novel paradigm of lineage segregation in the mammary gland and prostate. The lab was pioneered in using mouse genetics to identify the cancer cell of
origin of epithelial cancers. They identified the cancer cell of origin and the mechanisms regulating the early steps of tumor initiation in skin basal cell
carcinoma, skin squamous cell carcinoma and mammary tumors. They developed novel approaches to unravel the mode of tumour growth within their natural
environment and to understand the mechanisms regulating cancer stem cell functions. 

Location : Bâtiment GE, aile G2 4
Address : CP637 - Route de Lennik, 808 - 1070 Bruxelles
Phone number : +32 2 555 30 15
E-mail :
Web site :

Frascati domains:

 • 3.1 Basic medicine

Disciplines CRef :

 • Biomedical sciences

 • Cancerology

 • Cell biology

 • Cellular genetics

 • Molecular biology

 • Molecular genetics

Spin-off related of the unit :

 • ChromaCure