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This project aims to evaluate and developed in vitro maturation technique and oocytes vitrification to improve the survival rate and the developmental competence of the oocytes after thawing. This project allows to develop alternation to the ovarian tissue cryopreservation procedure to preserve fertility. Ongoing study in human and mice also evaluated the safety and the efficiency of adapted ovarian stimulation protocol using letrozole for breast cancer patients in order to collect and vitrify oocytes by avoiding harmful effect of hormones on tumoral progression during treatment.
• F.R.S.-FNRS et Fonds associés (hors FRIA)
• Financement de base institutionnel