This project aims to evaluate and developed in vitro maturation technique and oocytes vitrification to improve the survival rate
and the developmental competence of the oocytes after thawing. This project allows to develop alternation to the ovarian tissue
cryopreservation procedure to preserve fertility. Ongoing study in human and mice also evaluated the safety and the efficiency of
adapted ovarian stimulation protocol using letrozole for breast cancer patients in order to collect and vitrify oocytes by avoiding
harmful effect of hormones on tumoral progression during treatment.