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Genetics and ADHD: complementary approaches of case-control association studies and trios with exploration of the relationship between genotype-intermediate phenotype and imaging

Units : Neuropsychology and Functional Neuroimaging Research Unit | ULB684

Description :

FRSM 3.4.516.08 .F. Attention-deficit hyperactivity disorder (ADHD) is a multifactorial pathology with complex determinism
affecting between 3 and 5% of school-aged children. Alterations of executive functions observed at the clinicial level are probably
subtended by dysfunctions in dopaminergic and noradrenergic systems. Neurocognitive measurements associated with neuroimaging are
promising tools to explore new 'intermediate phenotypes' in the genetic investigation of the ADHD. Here, we aim at identifying
vulnerability genes in ADHD, looking at novel phenotypes by using neuropsychology and functional neuroimaging (IRMf and MEG) techniques.
Main promotor: I. Massat (Erasme hospital, ULB), associated promotor P. Peigneux

List of persons in charge :

  • MASSAT Isabelle

  • SLAMA Hichem

List of lessors :

  • Fonds associés (toutes subventions, y compris la Loterie Nat.)