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The quantitative interpretation of biological data requires the use of computer assisted approaches. A first approach consists of the statistical analysis of data in order to support relevance and significance of biological observations. A second approach deals with the elaboration and the computer simulation of models in order to test the validity of intuitively proposed schemas of regulation pathways. Theoretical studies have been especially conducted in the field of second messenger-controlled cascades (cyclic AMP, InsP3 , Ca2+) and receptor activation (TSH receptor, InsP3-receptor-Ca2+-channel).
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