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This project is devoted to the functional analysis of microtubules, a component of the cytoskeleton. We study in cellular models the modification in the organisation and transport functions of neuronal microtubules induced by changes in phosphorylation of microtubule-associated proteins. These studies are performed using cellular time lapse imaging, immunocytochemistry, electron microscopy and biochemical analysis of proteins.
• Fonds associés (toutes subventions, y compris la Loterie Nat.)