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Units : Laboratory of Histology | ULB598
This research project is devoted to the analysis of the etiopathogeny of Alzheimer's disease, a frequent neurodegenerative disease associated to brain aging. We study the cellular lesions of the disease in brain tissue of patients, and in cellular and transgenic models reproducing these lesions. These experimental models are analyzed by histological and biochemical methods, with the aim of investigating functional changes of keys-proteins (tau proteins, APP protein) involved in the development of the disease and how these proteins interact to induce cellular lesions of Alzheimer's disease. These models are also used to test potential therapeutic approachs interfering with the formation of the cellular lesions.
• Fonds associés (toutes subventions, y compris la Loterie Nat.)
• Autres ressources extérieures