Units

Laboratory of translational research, campus Brugmann

Person in charge of the Unit : Oui

The unit consists of different research groups: 1) Laboratory of experimental immunology (F Corazza); 2) Clinic of Immunoallergology (O. Michel, VI Doyen);  3) Physiopathology of bone and calcium metabolism:  regulation of bone remodeling  and the role of the Parathyroid-hormone Related Peptide in its regulation (P. Bergmann, N. Nijs, R. Karmali); bone mass measurements in metabolic bone diseases (coll. with the dept of Nuclear Medicine (A.S. Hambye), the Dept of medicine (J.J. Body, S. Cappelle) and the Clinic of Rheumatology, A. Peretz); 4) Experimental surgery: grafts of foetal organs (V. Coulic, with the collaboration of the Dept of Surgery and the Laboratory of Pathology); 5) Clinical Research Unit (A. Peretz, T. Besse): conception, organization and gestion of clinical studies.

Projetcs

Diagnosis and investigation of neuro-muscular diseases

The neuromuscular pathology unit bas developed technics to identify the membrane proteins linked to different muscular dystrophies, like dystrophin, the lack of which is responsible of Duchenne myopathy. These technics are used currently for the immuno- cytochemical djagnosis of myopathjes. The quantification by immunoblotting of these proteins will allow to detect affections caused, not by their absence, but by a quantitative deficit or a decrease of their length.

PICABO

 Research projet ailing to develop and validate a  Point of Care Test (POCT) medical device  to perform, at the patient bedside, a double verification of the blood group of the patient and the blood bag to be transfused

Etude de l'inflammation et de l'immunité innée dans différents modèles cliniques

Developpement de techniques d'immunohematologie visant l'amelioration de la sécurité transfusionnelle