Units

Organic Chemistry
Person in charge of the Unit : Oui
The Laboratory of Organic Chemistry is active in organic chemistry in a broad sense, with research programs going from the development of new processes in organic chemistry and copper catalysis, the synthesis of bioactive/natural products, medicinal chemistry and the design, synthesis and study of molecular receptors derived from calix[6]arenes. We are indeed interested in the synthesis of molecular receptors derived from calix[6]arenes and the study of their host-guest properties toward neutral or charged species (metal ions, ammonium ions, anions). Macrocyclization reactions are used as the key-step for the syntheses of the receptors. The molecular recognition mechanisms are studied thanks to NMR spectroscopy. The receptors are then applied in the self-assembly of molecular objects, in chiral recognition, in catalysis, in surface modification, and in the design of modified electrodes or fluorescent molecular probes. Another part of our research is focused on the development of new processes and reagents in organic synthesis. One of the main area of research of this program is based on the use of copper catalysis and copper-mediated transformations. More specifically, we have been involved in the use of copper-catalysis in the synthesis of natural and/or bioactive products, for the development of new processes and reagents in organic synthesis and, more recently, in the development of new copper-catalyzed polymerization processes, all these research programs being strongly interconnected. We are in addition involved in the development of new processes based on new reagents or chemical intermediates.Moreover, the Laboratory of Organic Chemistry develops the synthesis of molecules of biological interest in collaboration with other groups from academia and industry.
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