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Biologie du Noyau

Faculté des Sciences | Biologie moléculaire

(Code: ULB725)


Responsable de l'unité : FAHRENKROG Birthe.

Nuclear pore complexes (NPCs) are large protein assemblies that perforate the double membrane of the nuclear envelope (NE). They mediate all trafficking
between the nucleus and the cytoplasm of interphase cells and are composed of a set of different proteins, known as nucleoporins. Nucleoporins frequently
have additional functions in, for example, chromatin organisation, transcription and cell cycle progression, which are mainly independent of nuclear
transport. Therefore, nucleoporins are key players in overall nuclear organisation and intact nuclear organisation is critical for normal cell function. Alterations
in nuclear organisation in turn are, for example, hallmarks of cancer cells. Our aim is to understand the role of certain nucleoporins in cell cycle
regulation and tumour development.

Campus : Campus de Charleroi
I.B.M.M.
Campus de Rhode-St-G
Localisation : IBMM- Campus de Gosselies- bâtiment A - 4ème étage EST (A.E.4.108)
Adresse : CP300
Téléphone : +32-2-650.99.51/97.93
Fax : +32-2-650.99.50
Email : bfahrenk@ulb.ac.be
Site Web : http://www.ulb.ac.be/ibmm/bio-nucleus.html


Domaine de l'unité :


 • Immunologie