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Department of Pathology

Faculty of Medicine | Erasme Campus

Interfaculty institutes | U-CRC: ULB Cancer Research Center

(Code: ULB724)

Person in charge of the unit : SALMON Isabelle.

The main research themes of the laboratory focus on the identification and validation of new biomarkers in human cancers with diagnostic, prognostic and
theragnostic purposes. The research activities combine fundamental and clinical aspects. For more than 15 years, our investigations have been focused on
protein biomarkers in human tissue samples, animals and in vitro models. Immunohistochemistry (IHC) plays an essential role in the validation of these
biomarkers because, as opposed to other biochemical approaches, this technology enables morphological control and thus protein localization at histological and
cellular levels. A close collaboration with the Laboratory of Image Synthesis and Analysis (LISA, Ecole polytechnique, U.L.B., allows us
to develop standardized tools for characterizing protein expression by using the multiple abilities provided by digital image analysis. From this
collaboration was created the interfaculty unit, DIAPath (Digital Image Analysis in Pathology,, which is included
in the Center for Microscopy and Molecular Imaging (CMMI, Biopark of Gosselies, know-how in biomarkers is often requested by other
university and biotech research teams. These collaborations lead us to analyse human tumours from many origins as well as pathologic tissues from other diseases,
such as inflammatory diseases, graft-versus-host or diabetes.

Location : Hôpital Erasme ULB - Hôpital de jour (2ème étage)
Phone number : +32-2-555.31.15
Fax : +32-2-555.47.90
E-mail :
Web site :

Disciplines CRef :

 • Cancerology

 • Histopathology

 • Molecular biology