LISA - Image Analysis
LISA (Laboratory of Image Synthesis and Analysis) brings together expertise in image processing and analysis, pattern recognition, image synthesis and virtual reality. Its LISA-IA unit focuses on the fields of image analysis and pattern recognition and develops new methods for 2D and 3D object segmentation, recognition or tracking, multi-modal image registration, as well as machine and deep learning methods for signal and image processing. In the latter context, research is being carried out on the ability to deal with imperfect (weak or noisy) annotations and on methods of evaluating algorithms in such situations where the ground truth is not available.
Developed algorithms are related to biomedical and industrial applications. Following a problem-centered approach, the unit tackles all hardware and software aspects of the chain in multidisciplinary teams (MDs, biologists, engineers, computer scientists, mathematicians, as well as art historians and archaeologists) over multi-institutional collaborations to deliver functional applications. The research is funded both by institutional/public funds and industry collaborations. LISA's achievements include one patent, several highly cited biomedical papers, implementation of acquisition and thermoregulation devices for live cell imaging, multi-media event organization and international cultural heritage projects.
Whole slide imaging and analysis in digital pathology
Tissue-based biomarker characterization from whole slide image analysis using machine and deep learning and image registration.
This also includes the development of methods able to deal with imperfect (weak or noisy) annotations and methods of evaluating algorithms in such situations where the ground truth is not available
This research is carried out in close collaboration with the Pathology Department of the Erasme hospital and the DIAPath pole (https://www.cmmi.be/?page_id=12) of the Center for Microscopy and Molecular Imaging (CMMI, Biopark of Gosselies, ULB).
PROTHER-WAL : Proton Therapy Research in Wallonia
Image acquisition and processing for planning and monitoring proton therapy treatment (WP4)
From macro (in vivo) to micro (histology) for preclinical animal model, involving image co-registration and quantitative analysis of tissue-based biomarkers
Aims: analysis of treatment effects on tumor (microenvironment, healthy tissue, ...), validation of PET/IRM tracers