Units

Photochemistry

Person in charge of the Unit : Oui

The research developed in the Laboratory of Organic Chemistry and Photochmeistry (COP) covers several aspects: design and synthesis of novel mono- and polynuclear Ru(II) complexes with polyazaaromatic ligands nanometer sized, design and synthesis of oligometallic and dendritic metallic complexes, study and development of novel potential anti-cancer drugs, activated under illumination and based on metallic compounds, development of metallic photoprobes and photoreagents of DNA, new molecular tools for the study of DNA, interaction of metallic complexes with nucleic acids, design and synthesis of Ru derivatized oligonucleotides for the anti-sens or anti-gene strategy, and for study of networks, photochemistry of Ru(II) complexes in the presence of amino acids, oligopeptides and proteins, synthesis of Rh(III), Ir(III), Cu(I), Cu(II) complexes as novel materials with particular optical or/and electronic properties, as well as the development and study of novel Cu(I) complexes used as photocatalysts for organic synthesis and carbon dioxyde photoreduction

Projetcs

Nanometric networks ''Ru(II) complexes - oligonucleotides''

Synthesis and study of photo-electron processes in networks ''Ru(II) complexes - oligonucleotides''

Biomolecular Engineering

European Associated Laboratory (ULB and LEDSS in Grenoble) in order to study the problems of specific recognition between small organic or metallic molecules and biological macromolecules

Therapeutical photochemistry

Therapeutical photochemistry

Coordination complexes as photoactivatable agents for biological applications

Coordination complexes as photoactivatable agents for biological applications

Study of Ru(II) complexes in the presence of amino acids, oligopeptides and proteins.

Study of the interactions and photoreactions of Ru(II) complexes with amino-acids, oligopeptides and oligonucleotides.

Novel DNA-targeted metal complexes as light-activated molecular tool in DNA biochemistry

Study of novel potential photo-active anti-cancer drugs, based on some Ru(II) complexes, examination of their effects on DNA

PhotoCop: sustainable photocatalysis with copper complexes

PhotoCop: sustainable photocatalysis with copper complexes - Research program: Innoviris: Coord: Gwilherm Evano

Cryo-Single Photon Counting

Single Photon Counting Equipment

Bio-inspired Organic Nanostructures: design and recognition

Bio-inspired Organic Nanostructures: design and recognition

Synthesis and photophysics of coordination dendrimers

Metal ions-nucleic acid interactions and anti-tumor drugs

Structural characterization of photo-adducts ''complex-DNA'' formed under visible illumination of Ru(II) complexes based on tetraazaphenanthrene ligands, in interact

Developing Ru(II) photo-activable complexes for the detection via light-up effect and covalent photo-addition to G-quadruplexes

Developing Ru(II) photo-activable complexes for the detection via light-up effect and covalent photo-addition to G-quadruplexes

Synthesis and study of photoactivatable and vectorized supramolecular systems

Synthesis and study of photoactivatable and vectorized supramolecular systems, in collaboration with Eric Defrancq and Didier Boturyn from the University of Grenoble