Inventaire
Site en français
BOURGUIGNON Mathieu



Units

LCFC

The LCFC aims to group within the same structure the use for research purposes of brain mapping equipments, including magnetoencephalography (MEG), magnetic resonance imaging (MRI), and positron emission tomography (PET). The laboratory is directed by Serge Goldman et Patrick Van Bogaert, respectively director and co-director of a board composed by one delegate of the seven departments of Hôpital Erasme implicated in the management and use of these equipments:  Neurology, Neurosurgery, Nuclear Medicine, Psychiatry, Paediatric Neurology, Neuroradiology and Neuropsychology. LCFC has collaboration with laboratories of the Faculty of Psychology of the ULB for some research topics. More specifically, research on specific language impairment and on impact of epileptic activities on cognition and language is performed in collaboration with UR2NF (Neuropsychology and Functional Neuroimaging Research Unit,) whereas research on the neural bases of learning with and without consciousness is performed in collaboration with SRSC (Consciousness, Cognition and Computation Group). The study of the respective impacts of MEG and EEG-fMRI on the presurgical evaluation of epileptic patients candidates to surgery is performed in collaboration with the centres of reference for refractory epilepsy of Hôpital Erasme and Universitaire Ziekenhuis Gent.

Laboratory for Functional Anatomy

The Laboratory for Functional Anatomy (LAF) is a research group dedicated to human and animal anatomy and embryology.  
The LAF works in close collaboration with the Laboratory of Anatomy Biomechanics and Organogenesis (Faculty of Medicine), which benefits from the same infrastructure. Several research themes are also developed jointly. 

Research in the LAF is structured around complementary themes:  
- biomechanics, modeling and functional assessment  
- macroscopic and microscopic anatomy 
- embryology and teratology  
- forensic medicine and forensic anthropology  
- HOX genes and ovarian function  
- neurobiomechanics


Laboratory of Anatomy, Biomechanics and Organogenesis

Education - Our LABO teaches anatomy to students of various programs, including medicine, dental sciences, veterinary sciences, physical therapy, occupational therapy, bioengineering, sports, nursing, pharmacy, medical biology and arts. Moreover, LABO members also teach human embryology. Research - The LABO is active in several fields thanks to its multidisciplinary staff and expertise: Biomechanics, Anatomy, Organogenesis, Embryology, Veterinary Sciences and Legal Medicine. State-of-the-art equipment is available. Clinics - The Center for Functional Evaluation (or CFE) organised by LABO offers patients, and their therapists, all services for following-up of locomotor and gesture disabilities linked to a variety of disorders (orthopeadics, neurology, etc). Clinical research is also performed at LABO. Logistics - The LABO is taking part in the organisation of various structures and international scientific events.

Projetcs

Neurobiomechanics - beta oscillations

Beta oscillations of the sensorimotor cortex are the hallmark of sensorimotor brain function, reflecting motor abilities and neurological health. Their characterization usually requires the recording of brain activity using sophisticated and expensive equipment. Drawing on the results of fundamental research, the present project aims to develop and characterize a method for measuring a reflection of these oscillations in readily available signals, such as muscle activity or recordings of mechanical hand strength. He will then assess the method's potential for monitoring Parkinson's disease, as well as rehabilitation and recovery from stroke. Future applications are also planned in basic research, as well as in the assessment and monitoring of schizophrenia and autism spectrum disorders.
This research is funded by the WEL Research Institute.

Neurobiomechanics - beta oscillations

Beta oscillations of the sensorimotor cortex are the hallmark of sensorimotor brain function, reflecting motor abilities and neurological health. Their characterization usually requires the recording of brain activity using sophisticated and expensive equipment. Drawing on the results of fundamental research, the present project aims to develop and characterize a method for measuring a reflection of these oscillations in readily available signals, such as muscle activity or recordings of mechanical hand strength. He will then assess the method's potential for monitoring Parkinson's disease, and for monitoring rehabilitation and recovery from stroke. Future applications are also planned in basic research, as well as in the assessment and monitoring of schizophrenia and autism spectrum disorders. 

Neurobiomechanics - postural control

This project investigates the neural mechanisms underlying postural control and multisensory integration, focusing on how the brain integrates visual, proprioceptive and vestibular data to maintain balance. It aims to identify cortical markers of postural control, link variability in sensory weighting to patterns of brain activity, and characterize altered sensory reweighting in children with developmental coordination disorder, in the elderly, and in individuals with vestibular disorders. Using EEG, force platforms and novel methodologies, the project will explore how brain activity is coupled to postural and muscular control, and how this coupling varies as a function of environmental constraints.
The project aims to deepen our understanding of the etiology of different conditions that can affect postural control, and to contribute to the development of potential diagnostic and therapeutic tools.

Neurobiomechanics - postural control

This project investigates the neural mechanisms underlying postural control and multisensory integration, focusing on how the brain integrates visual, proprioceptive and vestibular data to maintain balance. It aims to identify cortical markers of postural control, link variability in sensory weighting to patterns of brain activity, and characterize altered sensory reweighting in children with developmental coordination disorder, in the elderly, and in individuals with vestibular disorders. Using EEG, force platforms and novel methodologies, the project will explore how brain activity is coupled to postural and muscular control, and how this coupling varies as a function of environmental constraints. 
The project aims to deepen our understanding of the etiology of different conditions that can affect postural control, and to contribute to the development of potential diagnostic and therapeutic tools.