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Self-sealing, anti-infectious wound dressing materials based on chitin hydrogel

Units : Biomass Transformation Lab | ULB831

Description :

Currently, there is an increasing trend on design and development of new wound healing/sealing materials. The focus is to use
biobased materials such as chitin and its derivatives to synthesise wound healing/sealing materials with the ability to enhance the
healing process at the molecular and cellular level. Chitin is an inexpensive and abundant polymer of linear 1,4
N-acetyl-D-glucosamine residues which is largely found in the exoskeleton of crustaceans shells as well as the cell walls of fungi and yeast. We
aimed to transform and utilise the chitooligosaccharides from the green photocatalysis process of chitin for the development of wound
healing hydrogel for biomedical applications. In this project we adopt catechol chemistry as a versatile and biocompatible green
method for the surface functionalization. With this regard, partially cross-linked catechol functionalized chitin will exhibit an
immediate sol-gel transition, resulting in sealing of the injured tissue and prevention of bleeding. 

List of persons in charge :

  • SHAVANDI Mohammadamin